IRAK3 polyclonal, anti-human, mouse

Background:
This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants.

Synonyms: ASRT5, IRAKM

Cellular Location: Nucleus

Immunogen:
Recombinant protein of human IRAK3

Gene Symbol: IRAK3

Gene ID: 11213

Swiss prot: Q9Y616

Calculated MW: 68kDa

Recommended dilution:
WB 1:500-2000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.