IRAK4 Polyclonal Antibody

Background:
This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.

Research Area: Cancer, Cardiovascular, Immunology, Signal Transduction

Synonyms:
IL-1 receptor-associated kinase 4, Interleukin 1 receptor associated kinase 4 mutant form 1, Interleukin-1 receptor-associated kinase 4, Interleukin1 receptor associated kinase 4, IPD1, IRAK 4, IRAK-4, IRAK4, IRAK4 mutated form 1, IRAK4, LOC 51135, NY REN 64, NY REN 64 antigen, NY-REN-64, REN64, Renal carcinoma antigen NY-REN-64

Immunogen: Recombinant protein of human IRAK4

Swissprot: Q9NWZ3
Gene Accession: BC013316

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.6 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-34469/sc-34470/sc-99154