IREB2 polyclonal (Center), anti-human
€0.00
In stock
SKU
AC-AP12657C
Catalog Number: AC-AP12657C
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB30212
Applications: FC, IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB30212
Applications: FC, IHC-P, WB
Datasheet
Request Information
Background:
IREB2 is a RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.
Other Names:
Iron-responsive element-binding protein 2, IRE-BP 2, Iron regulatory protein 2, IRP2, IREB2
Target/Specificity:
This IREB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 201-230 amino acids from the Central region of human IREB2.
Antigen Region:
201-230
Antigen Type: Synthetic Peptide
Gene Name: IREB2
Gene ID: 3658
Primary Accession: P48200
NCBI Accession: NP_004127.1
Other Accession: Q62751; B3VKQ2; Q811J3; NP_004127.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
IREB2 is a RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.
Other Names:
Iron-responsive element-binding protein 2, IRE-BP 2, Iron regulatory protein 2, IRP2, IREB2
Target/Specificity:
This IREB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 201-230 amino acids from the Central region of human IREB2.
Antigen Region:
201-230
Antigen Type: Synthetic Peptide
Gene Name: IREB2
Gene ID: 3658
Primary Accession: P48200
NCBI Accession: NP_004127.1
Other Accession: Q62751; B3VKQ2; Q811J3; NP_004127.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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