IRF-3 (phospho Ser386) Polyclonal Antibody

Background:
interferon regulatory factor 3(IRF3) Homo sapiens This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011],

Alternative Names:
IRF3, Interferon regulatory factor 3, IRF-3

Immunogen: The antiserum was produced against synthesized peptide derived from human IRF-3 around the phosphorylation site of Ser386. AA range:352-401

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 55

GeneID: IRF3

Storage: -20°C/1 year

NOTE: For Research Use Only