IRF1 Polyclonal Antibody

Background:
IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion.

Research Area: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling

Synonyms:
Interferon regulatory factor 1, Interferon regulatory factor 1 isoform +I9, Interferon regulatory factor 1 isoform d78, Interferon regulatory factor 1 isoform delta4, Interferon regulatory factor 1 isoform delta7, IRF 1, IRF-1, IRF1, IRF1, MAR, MAR1

Immunogen: Synthetic peptide of human IRF1

Swissprot: P10914
Gene Accession: NP_002189

Calculated MW: 37 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-640/sc-13041/sc-497/sc-137061