IRF2 polyclonal, anti-human, mouse, rat
€455.00
In stock
SKU
AC-ABO11126
Catalog Number: AC-ABO11126
Size: 100 µg
Isotype: Rabbit IgG
Applications: WB
Datasheet
Request Information
Size: 100 µg
Isotype: Rabbit IgG
Applications: WB
Datasheet
Request Information
Description: Rabbit IgG polyclonal antibody for Interferon regulatory factor 2(IRF2) detection. Tested with WB in Human;Mouse;Rat.Protein Name: Interferon regulatory factor 2(IRF-2)
Protein Function:
Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation. .
Other Names: Interferon regulatory factor 2, IRF-2, IRF2
Subcellular Localization: Nucleus.
Tissue Specificity: Expressed throughout the epithelium of the colon. Also expressed in lamina propria. .
Gene ID: 3660
Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human IRF2(249-266aa RPHWRKRNIEGKQYLSNM), identical to the related rat sequence and different from the related mouse sequence by one amino acid.
Calculated MW: 39354
Purification: Immunogen affinity purified.
Format: Lyophilized
Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Concentration (mg/ml): Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
Protein Function:
Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation. .
Other Names: Interferon regulatory factor 2, IRF-2, IRF2
Subcellular Localization: Nucleus.
Tissue Specificity: Expressed throughout the epithelium of the colon. Also expressed in lamina propria. .
Gene ID: 3660
Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human IRF2(249-266aa RPHWRKRNIEGKQYLSNM), identical to the related rat sequence and different from the related mouse sequence by one amino acid.
Calculated MW: 39354
Purification: Immunogen affinity purified.
Format: Lyophilized
Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Concentration (mg/ml): Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
| Is Featured? | No |
|---|
Write Your Own Review