IRF3 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS6921
Background:
IRF-3 can inhibit cell growth and plays a critical role in controlling the expression of genes in the innate immune response. In unstimulated cells, IRF-3 is present in the cytoplasm. Viral infection results in phosphorylation of IRF-3 and leads to its translocation to the nucleus where it activates promoters containing IRF-3-binding sites.
Alternative Name:
IRF3, IRF-3, IRF3, Interferon regulatory factor 3
Application Dilution: WB: 1:500~1:1000, IHC/IF: 1:50~1:200
Specificity: IRF3 polyclonal antibody detects endogenous levels of IRF3 protein.
Immunogen:
Recombinant full length Human IRF3.
MW: ~ 47, 55 kDa
Swis Prot.: Q14653
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
IRF-3 can inhibit cell growth and plays a critical role in controlling the expression of genes in the innate immune response. In unstimulated cells, IRF-3 is present in the cytoplasm. Viral infection results in phosphorylation of IRF-3 and leads to its translocation to the nucleus where it activates promoters containing IRF-3-binding sites.
Alternative Name:
IRF3, IRF-3, IRF3, Interferon regulatory factor 3
Application Dilution: WB: 1:500~1:1000, IHC/IF: 1:50~1:200
Specificity: IRF3 polyclonal antibody detects endogenous levels of IRF3 protein.
Immunogen:
Recombinant full length Human IRF3.
MW: ~ 47, 55 kDa
Swis Prot.: Q14653
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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