IRF3 Polyclonal Antibody

Background:
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Research Area: Cancer, Epigenetics and Nuclear Signaling, Immunology

Synonyms:
IIAE7, Interferon regulatory factor 3, IRF 3, IRF-3, IRF3, IRF3, MGC94729

Immunogen: Recombinant human Interferon regulatory factor 3 protein

Swissprot: Q14653

Calculated MW: 47 kDa
Observed MW: 47 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.

Concentration: 2 mg/mL
Dilution: WB 1:500-1:1000, IHC 1:50-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.