IRF4 antibody (clone 2D1), anti-human
€435.00
In stock
SKU
AC-AT2545a
Catalog Number: AC-AT2545a
Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB, IF, E
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Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB, IF, E
Request Information AC-AT2545a">Request Information
Background:
The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.
Other Names:
Interferon regulatory factor 4, IRF-4, Lymphocyte-specific interferon regulatory factor, LSIRF, Multiple myeloma oncogene 1, NF-EM5, IRF4, MUM1
Antigen Type:
Recombinant Protein
Gene Name: IRF4
Gene ID: 3662
NCBI Accession: NP_001182215.1;NP_002451.2
Primary Accession: Q15306
Other Accession: NM_002460
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.
Other Names:
Interferon regulatory factor 4, IRF-4, Lymphocyte-specific interferon regulatory factor, LSIRF, Multiple myeloma oncogene 1, NF-EM5, IRF4, MUM1
Antigen Type:
Recombinant Protein
Gene Name: IRF4
Gene ID: 3662
NCBI Accession: NP_001182215.1;NP_002451.2
Primary Accession: Q15306
Other Accession: NM_002460
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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