IRF5 Polyclonal Antibody

Background:
This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Alternative promoter use and alternative splicing result in multiple transcript variants, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment.

Research Area: Cancer, Epigenetics and Nuclear Signaling, Immunology

Synonyms:
IRF5, SLEB10

Immunogen: Recombinant fusion protein of human IRF5 (NP_001092097.2).

Swissprot: Q13568
Gene ID: 3663

Calculated MW: 17 kDa/47 kDa/54 kDa/56 kDa/57 kDa
Observed MW: 56 kDa/60 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IF 1:50-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.