IRF6 monoclonal, anti-human, mouse, rat

Description: Anti-IRF6 Rabbit Monoclonal Antibody . Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Protein Function:
Probable DNA-binding transcriptional activator. Key determinant of the keratinocyte proliferation-differentiation switch involved in appropriate epidermal development (By similarity). Plays a role in regulating mammary epithelial cell proliferation (By similarity). May regulate WDR65 transcription (By similarity)..

Other Names: Interferon regulatory factor 6, IRF-6, IRF6

Clone Name(s):
Clone: GHD-9

Subcellular Localization: Nucleus. Cytoplasm. Translocates to nucleus in response to an activating signal..

Tissue Specificity: Expressed in normal mammary epithelial cells. Expression is reduced or absent in breast carcinomas..

Gene ID: 3664

Immunogen: A synthesized peptide derived from human IRF6

Calculated MW: 53130

Purification: Affinity-chromatography

Format: Liquid

Contents: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Concentration (mg/ml): Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Storage: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.