IRF6 polyclonal, anti-human, mouse

Background:
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants.

Synonyms: LPS, PIT, PPS, VWS, OFC6, PPS1, VWS1

Cellular Location: Nucleus Cytoplasm

Immunogen:
Recombinant protein of human IRF6

Gene Symbol: IRF6

Gene ID: 3664

Swiss prot: O14896

Calculated MW: 53kDa

Recommended dilution:
WB 1:200-1000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.