IRGM Polyclonal Antibody

Background:
This gene encodes a member of the p47 immunity-related GTPase family. The encoded protein may play a role in the innate immune response by regulating autophagy formation in response to intracellular pathogens. Polymorphisms that affect the normal expression of this gene are associated with a susceptibility to Crohn's disease and tuberculosis.

Research Area: Cancer, Cardiovascular, Metabolism, Immunology, Signal Transduction, Stem Cells

Synonyms:
IFI1, Iigp3, Iipg3, Immunity related GTPase family M protein 1, Immunity related GTPase family, M, Immunity-related GTPase family M protein 1, Immunity-related GTPase family M protein, Interferon inducible protein 1, Interferon-inducible protein 1, Irgm, IRGM, IRGM1, LPS-stimulated RAW 264.7 macrophage protein 47 homolog, LRG 47, LRG-47, LRG-47-like protein, LRG47, MGC149263, MGC149264

Immunogen: Recombinant protein of human IRGM

Swissprot: A1A4Y4
Gene Accession: BC128168

Calculated MW: 20 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: WB 1:200-1:1000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-168202