IRS (phospho-Ser616) (clone HIR-B1), anti-human antibody
€315.00
In stock
SKU
AC-ABV10082-100
Catalog Number: AC-ABV10082-100
Size: 100 µg
Host: Mouse IgG
Applications: WB, E
Datasheet
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Size: 100 µg
Host: Mouse IgG
Applications: WB, E
Datasheet
Request Information
Background:
Insulin receptor substrates (IRS) subtypes are responsible for several insulin related activities, such as glucose homeostasis, cell growth, cell transformation, apoptosis and insulin signal transduction. The balance between Ser/Thr phosphorylation of IRS has been demonstrated to be an important regulator of insulin signaling. IRS1 has also been shown to be constitutively activated in cancers such as breast cancer, Wilm’s tumors, and adrenal cortical carcinomas. Does not recognize IRS peptide NOT phosphorylated at Ser616 and will not recognize IRS peptide phosphorylated at Tyr183. Also does not react with riboflavin carrier protein which is known to have multiple phosphate groups.
Other Names:
IRS, phospho-IRS, Phospho-IRS (Ser616)
Primary Accession: P35568
Gene Name: IRS1
Gene ID: 3667
Concentration (mg/ml): 1.0 mg/ml
Insulin receptor substrates (IRS) subtypes are responsible for several insulin related activities, such as glucose homeostasis, cell growth, cell transformation, apoptosis and insulin signal transduction. The balance between Ser/Thr phosphorylation of IRS has been demonstrated to be an important regulator of insulin signaling. IRS1 has also been shown to be constitutively activated in cancers such as breast cancer, Wilm’s tumors, and adrenal cortical carcinomas. Does not recognize IRS peptide NOT phosphorylated at Ser616 and will not recognize IRS peptide phosphorylated at Tyr183. Also does not react with riboflavin carrier protein which is known to have multiple phosphate groups.
Other Names:
IRS, phospho-IRS, Phospho-IRS (Ser616)
Primary Accession: P35568
Gene Name: IRS1
Gene ID: 3667
Concentration (mg/ml): 1.0 mg/ml
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