IRS2 polyclonal, anti-human

Quantity: 100 µg

Background:
Insulin receptor substrate 2 (IRS2) is a protein that in humans is encoded by the IRS2 gene. It is mapped to 13q34. This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment. IRS2 is expressed in many cells, it may be essential for signaling by several receptor systems.

Description:
Rabbit IgG polyclonal antibody for Insulin receptor substrate 2 (IRS2) detection. Tested with WB in Human.

Synonyms:
Insulin receptor substrate 2 antibody, IRS 2 antibody, IRS-2 antibody, Irs2 antibody, IRS2_HUMAN antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human IRS2 recombinant protein (Position: D16-V200). Human IRS2 shares 88% amino acid (aa) sequence identity with mouse IRS2.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.