IRS2 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS71008
Background:
This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.
Alternative Name:
IRS-2,
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: IRS2 polyclonal antibody detects endogenous levels of IRS2 protein.
Immunogen:
Recombinant protein of human IRS2.
MW: ~ 137 kDa
Swis Prot.: Q9Y4H2
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.
Alternative Name:
IRS-2,
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: IRS2 polyclonal antibody detects endogenous levels of IRS2 protein.
Immunogen:
Recombinant protein of human IRS2.
MW: ~ 137 kDa
Swis Prot.: Q9Y4H2
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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