IRS2 Polyclonal Antibody

Background:
This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.

Research Area: Cancer, Cardiovascular, Metabolism, Signal transduction

Synonyms:
Insulin receptor substrate 2, IRS 2, IRS-2, Irs2, IRS2

Immunogen: Synthetic peptide of human IRS2

Swissprot: Q9Y4H2
Gene Accession: NP_003740

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: IHC 1:50-200, ELISA 1:2000-10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-1555/sc-8299