IRS2 Polyclonal Antibody

Background:
This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.

Research Area: Cancer, Cardiovascular, Metabolism, Signal transduction

Synonyms:
IRS2, IRS-2

Immunogen: Recombinant fusion protein of human IRS2 (NP_003740.2).

Swissprot: Q9Y4H2
Gene ID: 8660

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "IHC 1:50-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.