IRX5 Polyclonal Antibody

Background:
This gene encodes a member of the iroquois homeobox gene family, which are involved in several embryonic developmental processes. Knockout mice lacking this gene show that it is required for retinal cone bipolar cell differentiation, and that it negatively regulates potassium channel gene expression in the heart to ensure coordinated cardiac repolarization. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Research Area: Neuroscience,Epigenetics and Nuclear Signaling,Cardiovascular

Synonyms:
Iroquois Homeobox 5, Homeodomain Protein IRX-2A, Homeodomain Protein IRXB2, IRXB2, IRX2A, HMMS

Immunogen: Synthetic peptide of human IRX5

Swissprot: P78411
Gene Accession: NP005844

Calculated MW: 50 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.08 mg/mL
Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.