ISG15 Polyclonal Antibody

Background:
The protein encoded by this gene is a ubiquitin-like protein that is conjugated to intracellular target proteins upon activation by interferon-alpha and interferon-beta. Several functions have been ascribed to the encoded protein, including chemotactic activity towards neutrophils, direction of ligated target proteins to intermediate filaments, cell-to-cell signaling, and antiviral activity during viral infections. While conjugates of this protein have been found to be noncovalently attached to intermediate filaments, this protein is sometimes secreted.

Research Area: Cell Biology, Epigenetics and Nuclear Signaling

Synonyms:
G1P2, hUCRP, IFI 15, IFI15, Interferon alpha inducible protein, Interferon induced protein 15, Interferon induced protein IFI-15K, Interferon stimulated protein 15 kDa, Interferon, alpha-inducible protein (clone IFI-15K), Interferon-induced 15 kDa protein, Interferon-induced 17 kDa protein, Interferon-induced 17-kDa/15-kDa protein, IP17, ISG 15, ISG15, ISG15 ubiquitin like modifier, ISG15, Ubiquitin cross-reactive protein, Ubiquitin-like protein ISG15, UCRP

Immunogen: Fusion protein of human ISG15

Swissprot: P05161
Gene Accession: BC009507

Calculated MW: 18 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.5 mg/mL
Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.