ITGA2 polyclonal, anti-human, mouse, rat

Background:
This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants.

Synonyms: BR, CD49B, GPIa, HPA-5, VLA-2, VLAA2

Cellular Location: Membrane Single-pass type I membrane protein

Immunogen:
Recombinant protein of human ITGA2

Gene Symbol: ITGA2

Gene ID: 3673

Swiss prot: P17301

Calculated MW: 129kDa

Recommended dilution:
WB 1:500-2000, IHC 1:100-200, IF 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.