CD41a (ITGA2B) polyclonal, anti-human, mouse

CD41a (ITGA2B) polyclonal, anti-human, mouse

€388.00
In stock
SKU
BS7664
Catalog Number: BS7664
Size: 50 ul, 100 ul
Isotype: rabbit IgG
Applications: WB, IF

Datasheet
Background:
ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.

Alternative Name:
antigen CD41, BDPLT16, BDPLT2, CD41, cd41 antigen, CD41a, cd41b, form 2, gp2b, GPalpha IIb, gpalphaiib, gpiib, GT, gta, HPA3, Integrin alpha 2b, Integrin alpha IIb, Integrin alpha-IIb light chain, Integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41), ITA2B_HUMAN, ITGA2B, ITGAB, platelet fibrinogen receptor alpha, platelet fibrinogen receptor, alpha subunit, platelet glycoprotein IIb of IIb/IIIa complex, platelet membrane glycoprotein iib, platelet specific antigen bak,

Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200

Specificity: ITGA2B polyclonal antibody detects endogenous levels of ITGA2B protein.

Immunogen:
Recombinant full length Human ITGA2B.

MW: ~113 kDa

Swis Prot.: P08514

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.
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