ITGA3 Blocking Peptide (C-term)
€363.00
In stock
SKU
AC-BP21353b
Background:
Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha- 3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.
Other Names:
Integrin alpha-3, CD49 antigen-like family member C, FRP-2, Galactoprotein B3, GAPB3, VLA-3 subunit alpha, CD49c, Integrin alpha-3 heavy chain, Integrin alpha-3 light chain, ITGA3, MSK18
Target/Specificity:
The synthetic peptide sequence is selected from aa 875-889 of HUMAN ITGA3
Gene Name: ITGA3
Gene ID: 3675
Primary Accession: P26006
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha- 3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.
Other Names:
Integrin alpha-3, CD49 antigen-like family member C, FRP-2, Galactoprotein B3, GAPB3, VLA-3 subunit alpha, CD49c, Integrin alpha-3 heavy chain, Integrin alpha-3 light chain, ITGA3, MSK18
Target/Specificity:
The synthetic peptide sequence is selected from aa 875-889 of HUMAN ITGA3
Gene Name: ITGA3
Gene ID: 3675
Primary Accession: P26006
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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