ITGA3 Polyclonal Antibody

Background:
ITGA3, also named as MSK18, CD49c, GAPB3 and FRP-2, belongs to the integrin alpha chain family. It is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. ITGA3 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. ITGA3 is highly concentrated in epithelial cells where it strongly adheres to Laminin-5 and Laminin-5 induced rapid adhesion can be blocked by antibodies against the alpha-3 integrin subunit. It can be cleaved into heavy chain(840aa) and light chain(176aa). This antibody can recognize the heavy chain.

Research Area: Cancer, Signal Transduction

Synonyms:
AA407068, Antigen identified by monoclonal J143, CD49 antigen like family member C, CD49 antigen-like family member C, CD49c, CD49c antigen, FLJ34631, FLJ34704, FRP 2, FRP-2, FRP2, Galactoprotein B3, GAP B3, GAPB3, Integrin alpha 3, Integrin alpha-3 light chain, Integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor), ITA3, ITGA 3, Itga3, MSK18, VCA 2, VCA2, Very late activation protein 3 receptor alpha 3 subunit, VL3A, VLA 3 alpha chain, VLA 3 subunit alpha, VLA-3 subunit alpha, VLA3a

Immunogen: Synthetic peptide of human ITGA3

Swissprot: P26006
Gene Accession: NP002195

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.32 mg/mL
Dilution: IHC 1:40-1:200, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.