ITGA5 (clone 10F6), anti-human
€478.00
In stock
SKU
252937
Protein Family: CAM Ligands, Cell Adhesion Molecules, Cellular Antigens, Receptors and Channels
Pathway and Disease: Cancers, Cell Communication, Cell Motility, Immune System, Signaling Molecules and Interaction
Description:
ITGA5 (Integrin alpha-5) is a 115-kDa transmembrane glycoprotein. Integrin alpha-5 subunit is the common alpha-5 chain of the very late antigen (VLA) forming a non-covalent heterodimeric complex with the integrin beta-1 subunit, a receptor for fibrinogen and extracellular matrix proteins such as fibronectin. Alpha-5/beta-1 integrin is an important adhesion molecule involved in cell-cell and cell-extracellular matrix interactions by recognizing the RGD canonical sequence in ligands. In addition to adhesion, integrins are known to participate in cell-surface mediated signaling.
Alternate Names: Integrin alpha-5, Fibronectin receptor subunit alpha, Integrin alpha-F, VLA-5, CD49 antigen-like family member E, CD49e, ITGA5, FNRA
Application Notes: WB: 1:500-1:2000; FC: 1:200-1:400
Accession No.: P08648
Antigen: Purified recombinant fragment of human ITGA5 expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Cancers, Cell Communication, Cell Motility, Immune System, Signaling Molecules and Interaction
Description:
ITGA5 (Integrin alpha-5) is a 115-kDa transmembrane glycoprotein. Integrin alpha-5 subunit is the common alpha-5 chain of the very late antigen (VLA) forming a non-covalent heterodimeric complex with the integrin beta-1 subunit, a receptor for fibrinogen and extracellular matrix proteins such as fibronectin. Alpha-5/beta-1 integrin is an important adhesion molecule involved in cell-cell and cell-extracellular matrix interactions by recognizing the RGD canonical sequence in ligands. In addition to adhesion, integrins are known to participate in cell-surface mediated signaling.
Alternate Names: Integrin alpha-5, Fibronectin receptor subunit alpha, Integrin alpha-F, VLA-5, CD49 antigen-like family member E, CD49e, ITGA5, FNRA
Application Notes: WB: 1:500-1:2000; FC: 1:200-1:400
Accession No.: P08648
Antigen: Purified recombinant fragment of human ITGA5 expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
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