ITGA5 polyclonal, anti-human

Background:
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.

Synonyms: CD49e, FNRA, VLA-5, VLA5A, integrin alpha-5

Cellular Location: Cytoplasm

Immunogen:
A synthetic peptide of human ITGA5

Gene Symbol: ITGA5

Gene ID: 3678

Swiss prot: P08648

Calculated MW: 115kDa

Recommended dilution:
IHC 1:20-50

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.