ITGA7 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Integrin alpha-7 is a protein that in humans is encoded by the ITGA7 gene. This gene is mapped to 12q13.2. The protein encoded by this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. They mediate a wide spectrum of cell-cell and cell-matrix interactions, and thus play a role in cell migration, morphologic development, differentiation, and metastasis. This protein functions as a receptor for the basement membrane protein laminin-1. It is mainly expressed in skeletal and cardiac muscles and may be involved in differentiation and migration processes during myogenesis. Defects in this gene are associated with congenital myopathy.

Description:
Rabbit IgG polyclonal antibody for Integrin alpha-7 (ITGA7) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
alpha 7 antibody, FLJ25220 antibody, Integrin alpha 7 antibody, Integrin alpha 7 chain antibody, Integrin alpha 7 heavy chain antibody, Integrin alpha 7 light chain antibody, Integrin alpha-7 70 kDa form antibody, ITA7_HUMAN antibody, ITGA 7 antibody, Itga7 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human ITGA7(1123-1139aa HAVKIPREDRQQFKEEK), identical to the related mouse sequence, and different from the related rat sequence by one amino acid.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human.
Predicted to work with: mouse, rat.

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.