ITGA7 Polyclonal Antibody

Background:
The protein encoded by this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. They mediate a wide spectrum of cell-cell and cell-matrix interactions, and thus play a role in cell migration, morphologic development, differentiation, and metastasis. This protein functions as a receptor for the basement membrane protein laminin-1. It is mainly expressed in skeletal and cardiac muscles and may be involved in differentiation and migration processes during myogenesis. Defects in this gene are associated with congenital myopathy. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Research Area: Cancer, Cardiovascular, Signal Transduction

Synonyms:
alpha 7, FLJ25220, Integrin alpha 7, Integrin alpha 7 chain, Integrin alpha 7 heavy chain, Integrin alpha 7 light chain, Integrin alpha-7 70 kDa form, ITA7, ITGA 7, Itga7

Immunogen: Synthetic peptide of human ITGA7

Swissprot: Q13683
Gene Accession: NP_002197

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.7 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-27706/sc-27710/sc-50431