ITGAE Polyclonal Antibody

Background:
Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation.

Research Area: Cancer, Immunology, Signal Transduction, Stem Cells

Synonyms:
A530055J10, alpha-E1, alpha-M290, aM290, Antigen CD103, CD 103, CD103, CD103 antigen, HML 1 antigen, HML-1 antigen, HML1 antigen, Human mucosal lymphocyte antigen 1, Human mucosal lymphocyte antigen 1, alpha subunit, Huminae, Integrin alpha E heavy chain, Integrin alpha E light chain, Integrin alpha E, epithelial-associated, Integrin alpha E1, Integrin alpha IEL, Integrin alpha M290, Integrin alpha-E heavy chain, Integrin alpha-IEL, Integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1, alpha polypeptide), Integrin, alpha E, ITAE, Itgae, MGC141996, MGC183601, Mucosal lymphocyte 1 antigen, Mucosal lymphocyte antigen 1

Immunogen: Recombinant protein of human ITGAE

Swissprot: P38570
Gene Accession: BC113436

Calculated MW: 130 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: WB 1:200-1:1000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-6606/sc-6607/sc-28662