ITGAM (clone 4A4B9), anti-
€0.00
In stock
SKU
BT-MCA2471
Catalog Number: BT-MCA2471
Size(s): 50μL, 100μL
Isotype: Mouse IgG1
Reactivity:
Application(s): IHC, ICC, FCM
Datasheet
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Size(s): 50μL, 100μL
Isotype: Mouse IgG1
Reactivity:
Application(s): IHC, ICC, FCM
Datasheet
Request Information
Background:
This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.
Research Area: Signal transduction, Stem cells, Neuroscience, Tags & cell markers, Immunology
Synonyms: CR3A, MO1A, CD11B, MAC-1, MAC1A, SLEB6
Immunogen: Purified recombinant fragment of human ITGAM (AA: 623-728) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
Storage:
4°C|-20°C for long term storage
This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.
Research Area: Signal transduction, Stem cells, Neuroscience, Tags & cell markers, Immunology
Synonyms: CR3A, MO1A, CD11B, MAC-1, MAC1A, SLEB6
Immunogen: Purified recombinant fragment of human ITGAM (AA: 623-728) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
Storage:
4°C|-20°C for long term storage
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