ITGAV polyclonal, anti-human, mouse

Background:
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.

Synonyms: CD51, MSK8, VNRA, VTNR

Cellular Location: Cytoplasm Membrane

Immunogen:
A synthetic peptide of human ITGAV

Gene Symbol: ITGAV

Gene ID: 3685

Swiss prot: P06756

Calculated MW: 116/112kDa

Recommended dilution:
IHC 1:50-100

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.