ITGAX Polyclonal Antibody

Background:
Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits. CD11c/Integrin alpha X is a type I transmembrane protein present on a variety of cells, including monocytes/macrophages, granulocytes, NK cells and dendritic cells. Integrin alpha X/beta 2 acts a receptor for fibrinogen and is important in monocyte adhesion and chemotaxis.

Research Area: Cancer, Immunology, Signal Transduction, Stem Cells

Synonyms:
95 alpha chain, 95, CD 11c, CD11 antigen like family member C, CD11 antigen-like family member C, CD11c, CD11c antigen, Complement component 3 receptor 4 subunit, CR4, Integrin alpha X, Integrin alpha X chain, Integrin alpha-X, Integrin aX, Integrin subunit alpha X, integrin, alpha X (antigen CD11C (p150), alpha polypeptide), integrin, alpha X (complement component 3 receptor 4 subunit, ITAX, ITGAX, LEU M5 alpha subunit, Leu M5, Leukocyte adhesion glycoprotein p150 95 alpha chain, Leukocyte adhesion glycoprotein p150, Leukocyte adhesion receptor p150 95, Leukocyte adhesion receptor p150, Leukocyte surface antigen p150 95 alpha subunit, Leukocyte surface antigen p150 alpha subunit, Myeloid membrane antigen alpha subunit, p150 95 integrin alpha chain, p150, p150/95, SLEB6

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse CD11c

Swissprot: P20702,Q9QXH4

Calculated MW: 120-150 kDa
Observed MW: 150 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Concentration: 0.98 mg/mL
Dilution: WB1:500-1:1000, IHC 1:100-1:300, IF 1:100-1:300

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Citation(s):
https://pubmed.ncbi.nlm.nih.gov/31332163/