ITGB1BP1 Polyclonal Antibody

Background:
The cytoplasmic domains of integrins are essential for cell adhesion. The protein encoded by this gene binds to the beta1 integrin cytoplasmic domain. The interaction between this protein and beta1 integrin is highly specific. Two isoforms of this protein are derived from alternatively spliced transcripts. The shorter form of this protein does not interact with the beta1 integrin cytoplasmic domain. The longer form is a phosphoprotein and the extent of its phosphorylation is regulated by the cell-matrix interaction, suggesting an important role of this protein during integrin-dependent cell adhesion. Several transcript variants, some protein-coding and some non-protein coding, have been found for this gene.

Research Area: Signal transduction

Synonyms:
Bodenin, DKFZp686K08158, ICAP 1, ICAP 1A, ICAP 1alpha, ICAP 1B, ICAP-1, ICAP-1A, ICAP-1alpha, ICAP-1B, ICAP1, ICAP1A, ICAP1B, Integrin beta 1 binding protein 1, Integrin beta-1-binding protein 1, Integrin cytoplasmic domain associated protein 1 alpha, Integrin cytoplasmic domain associated protein 1, Integrin cytoplasmic domain associated protein 1 beta, Integrin cytoplasmic domain-associated protein 1, ITBP1, ITGB1BP1

Immunogen: Fusion protein of human ITGB1BP1

Swissprot: O14713
Gene Accession: BC012264

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.84 mg/mL
Dilution: IHC 1:50-1:200, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.