ITGB2 antibody (clone 5F12), anti-human

ITGB2 antibody (clone 5F12), anti-human

€435.00
In stock
SKU
AC-AT2568a
Catalog Number: AC-AT2568a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, E
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Background:
The product of this gene belongs to the integrin beta chain family of proteins. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. This gene encodes the integrin beta chain beta 2. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene.

Other Names:
Integrin beta-2, Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta, Complement receptor C3 subunit beta, CD18, ITGB2, CD18, MFI7

Antigen Type:
Recombinant Protein

Gene Name: ITGB2
Gene ID: 3689
NCBI Accession: NP_000202.2;NP_001120963.1
Primary Accession: P05107
Other Accession: BC005861
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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