ITGB2 polyclonal, anti-human

ITGB2 polyclonal, anti-human

€0.00
In stock
SKU
AC-AP18109a
Catalog Number: AC-AP18109a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB38825
Applications: WB
Datasheet

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Background:
The product of this gene belongs to the integrin beta chain family of proteins. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. This gene encodes the integrin beta chain beta 2. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene.

Other Names:
Integrin beta-2, Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta, Complement receptor C3 subunit beta, CD18, ITGB2, CD18, MFI7

Target/Specificity:
This ITGB2 antibody is generated from rabbits immunized with a recombinant protein from the human ITGB2.

Antigen Type: Recombinant Protein

Gene Name: ITGB2
Gene ID: 3689
Primary Accession: P05107
NCBI Accession: NP_000202.2;NP_001120963.1
Other Accession: NP_000202.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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