ITM2B polyclonal (C-term), anti-mouse
€0.00
In stock
SKU
AC-AP13163b
Catalog Number: AC-AP13163b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB32712
Applications: WB, IHC-P
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB32712
Applications: WB, IHC-P
Datasheet
Request Information
Background:
Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form thecharacteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia.
Other Names:
Integral membrane protein 2B, Immature BRI2, imBRI2, Protein E25B, Transmembrane protein BRI, Bri, BRI2, membrane form, Mature BRI2, mBRI2, BRI2 intracellular domain, BRI2 ICD, BRI2C, soluble form, Bri23 peptide, Bri2-23, ABri23, C-terminal peptide, P23 peptide, ITM2B, BRI, BRI2
Target/Specificity:
This ITM2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 218-247 amino acids from the C-terminal region of human ITM2B.
Antigen Region:
218-247
Antigen Type: Synthetic Peptide
Gene Name: ITM2B
Gene ID: 9445
Primary Accession: Q9Y287
NCBI Accession: NP_068839.1
Other Accession: Q60HC1; NP_068839.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form thecharacteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia.
Other Names:
Integral membrane protein 2B, Immature BRI2, imBRI2, Protein E25B, Transmembrane protein BRI, Bri, BRI2, membrane form, Mature BRI2, mBRI2, BRI2 intracellular domain, BRI2 ICD, BRI2C, soluble form, Bri23 peptide, Bri2-23, ABri23, C-terminal peptide, P23 peptide, ITM2B, BRI, BRI2
Target/Specificity:
This ITM2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 218-247 amino acids from the C-terminal region of human ITM2B.
Antigen Region:
218-247
Antigen Type: Synthetic Peptide
Gene Name: ITM2B
Gene ID: 9445
Primary Accession: Q9Y287
NCBI Accession: NP_068839.1
Other Accession: Q60HC1; NP_068839.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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