ITM2C polyclonal (N-term), anti-human
€0.00
In stock
SKU
AC-AP17192a
Catalog Number: AC-AP17192a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB36714
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB36714
Applications: WB
Datasheet
Request Information
Background:
Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha-and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation (By similarity).
Other Names:
Integral membrane protein 2C, Cerebral protein 14, Transmembrane protein BRI3, CT-BRI3, ITM2C, BRI3
Target/Specificity:
This ITM2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-55 amino acids from the N-terminal region of human ITM2C.
Antigen Region:
27-55
Antigen Type: Synthetic Peptide
Gene Name: ITM2C
Gene ID: 81618
Primary Accession: Q9NQX7
NCBI Accession: NP_001012532.1;NP_001012534.1;NP_112188.1
Other Accession: Q4R540; NP_001012532.1; NP_001012534.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha-and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation (By similarity).
Other Names:
Integral membrane protein 2C, Cerebral protein 14, Transmembrane protein BRI3, CT-BRI3, ITM2C, BRI3
Target/Specificity:
This ITM2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-55 amino acids from the N-terminal region of human ITM2C.
Antigen Region:
27-55
Antigen Type: Synthetic Peptide
Gene Name: ITM2C
Gene ID: 81618
Primary Accession: Q9NQX7
NCBI Accession: NP_001012532.1;NP_001012534.1;NP_112188.1
Other Accession: Q4R540; NP_001012532.1; NP_001012534.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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