Endo180 polyclonal, anti-human, mouse, rat
€470.00
In stock
SKU
AC-AP73586
Catalog Number: AC-AP60870
Size: 100 µl
Host: Rabbit
Applications: WB, IF/IC
Datasheet
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Size: 100 µl
Host: Rabbit
Applications: WB, IF/IC
Datasheet
Request Information
Background:
May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover. May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs).
Other Names:
MRC2; CLEC13E; ENDO180; KIAA0709; UPARAP; C-type mannose receptor 2; C-type lectin domain family 13 member E; Endocytic receptor 180; Macrophage mannose receptor 2Urokinase-type plasminogen activator receptor-associated protein; UPAR-associated protein; Urokinase receptor-associated protein; CD280
Antigen Type: synthetic peptide
Antigen Type: MRC2
Gene ID: 9902
Primary Accession: Q9UBG0
May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover. May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs).
Other Names:
MRC2; CLEC13E; ENDO180; KIAA0709; UPARAP; C-type mannose receptor 2; C-type lectin domain family 13 member E; Endocytic receptor 180; Macrophage mannose receptor 2Urokinase-type plasminogen activator receptor-associated protein; UPAR-associated protein; Urokinase receptor-associated protein; CD280
Antigen Type: synthetic peptide
Antigen Type: MRC2
Gene ID: 9902
Primary Accession: Q9UBG0
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