ITPR1 Polyclonal Antibody

Background:
This gene encodes an intracellular receptor for inositol 1, 4, 5-trisphosphate. Upon stimulation by inositol 1, 4, 5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene.

Research Area: Cancer, Metabolism, Signal transduction

Synonyms:
4, 5-trisphosphate receptor, 5-trisphosphate receptor type 1, DKFZp313E1334, DKFZp313N1434, inositol 1 4 5 triphosphate receptor type 1, Inositol 1 4 5 trisphosphate Receptor Type 1, Inositol 1, InsP3R1, IP3, IP3 receptor, IP3 receptor isoform 1, IP3R 1, IP3R, IP3R1, ITPR 1, Itpr1, ITPR1, SCA15, SCA16, SCA29, Type 1 inositol 1 4 5 trisphosphate receptor, Type 1 inositol 1, Type 1 InsP3 receptor

Immunogen: Synthetic peptide of human ITPR1

Swissprot: Q14643
Gene Accession: NP_001093422

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.8 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-26382/sc-26381/sc-6093/sc-28614