ITPR3 polyclonal, anti-human

Background:
This gene encodes a receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. The receptor contains a calcium channel at the C-terminus and the ligand-binding site at the N-terminus. Knockout studies in mice suggest that type 2 and type 3 inositol 1,4,5-trisphosphate receptors play a key role in exocrine secretion underlying energy metabolism and growth.

Alternative Name:
IP3R, IP3R3

Application Dilution: WB: 1:500 - 1:2000

Specificity: ITPR3 polyclonal antibody detects endogenous levels of ITPR3 protein.

Immunogen:
Recombinant Protein of human ITPR3

MW: 280kDa

Swis Prot.: Q14573

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.