ITPR3 Polyclonal Antibody

Background:
This gene encodes a receptor for inositol 1, 4, 5-trisphosphate, a second messenger that mediates the release of intracellular calcium. The receptor contains a calcium channel at the C-terminus and the ligand-binding site at the N-terminus. Knockout studies in mice suggest that type 2 and type 3 inositol 1, 4, 5-trisphosphate receptors play a key role in exocrine secretion underlying energy metabolism and growth.

Research Area: Neuroscience, Signal transduction

Synonyms:
4, 5-trisphosphate receptor, 5-trisphosphate receptor type 3, FLJ36205, Inositol 1, Inositol 1, 4, 5 trisphosphate receptor type 3, InsP3R3, IP3 receptor, IP3 receptor isoform 3, IP3R 3, IP3R, IP3R3, ITPR 3, ITPR3, ITPR3, Type 3 inositol 1, Type 3 inositol 1, 4, 5 trisphosphate receptor, Type 3 InsP3 receptor

Immunogen: Synthetic peptide of human ITPR3

Swissprot: Q14573
Gene Accession: NP_002215

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.6 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-7277