ITPR3 Polyclonal Antibody

Background:
This gene encodes a receptor for inositol 1, 4, 5-trisphosphate, a second messenger that mediates the release of intracellular calcium. The receptor contains a calcium channel at the C-terminus and the ligand-binding site at the N-terminus. Knockout studies in mice suggest that type 2 and type 3 inositol 1, 4, 5-trisphosphate receptors play a key role in exocrine secretion underlying energy metabolism and growth.

Research Area: Neuroscience, Signal Transduction

Synonyms:
ITPR3, IP3R, IP3R3

Immunogen: Recombinant fusion protein of human ITPR3 (NP_002215.2).

Swissprot: Q14573
Gene ID: 3710

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IF 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.