JAG1 Polyclonal Antibody

Background:
The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.

Research Area: Cancer, Cardiovascular, Neuroscience, Stem cells

Synonyms:
JAG1, AGS, AGS1, AHD, AWS, CD339, HJ1, JAGL1, jagged 1

Immunogen: Recombinant fusion protein of human JAG1 (NP_000205.1).

Swissprot: P78504
Gene ID: 182

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IF 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.