JAG1 Polyclonal Antibody

Background:
The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.

Research Area: Cancer, Cardiovascular, Neuroscience, Stem Cells

Synonyms:
AGS, AHD, AWS, CD 339, CD339, CD339 antigen, Headturner, hJ1, Htu, Jag 1, Jag1, JAG1, Jagged 1, Jagged1 (Alagille syndrome), Jagged1, JAGL1, MGC104644, OTTHUMP00000030278, Protein jagged-1, Ser 1, Ser1, Serrate 1, Slalom

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Jagged1

Swissprot: Q9QXX0,Q63722

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Concentration: 140 μg/mL
Dilution: IHC 1:200-1:400

Storage:
Store at -20°C. Avoid freeze / thaw cycles.