Jagged 2 polyclonal, anti-human, rat

Quantity: 100 µg

Background:
Protein jagged-2, also known as SER2, is a protein that in humans is encoded by the JAG2 gene. It is mapped to 14q32.33. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Notch ligands Delta1 and JAG2 are subject to presenilin-dependent, intramembranous gamma-secretase processing, resulting in the production of soluble intracellular derivatives. JAG2 can promote the growth and dissemination of uveal melanoma cells.

Description:
Rabbit IgG polyclonal antibody for Protein jagged-2 (JAG2) detection. Tested with WB in Human, Rat.

Synonyms:
D12Ggc2e antibody, HJ 2 antibody, HJ2 antibody, JAG 2 antibody, JAG2 antibody, Jagged 2 precursor antibody, Jagged2 antibody, Protein jagged 2 antibody, SER2 antibody, Syndactylism antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human Jagged 2 recombinant protein (Position: R962-E1238). Human Jagged 2 shares 85% and 79% amino acid (aa) sequence identity with mouse and rat Jagged 2, respectively.E.coli-derived human Jagged 2 recombinant protein (Position: R962-E1238). Human Jagged 2 shares 85% and 79% amino acid (aa) sequence identity with mouse and rat Jagged 2, respectively.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.