JAK1 Rabbit polyclonal antibody, anti-human, mouse, rat

Background:
This gene encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The encoded kinase phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon-alpha/beta and interferon-gamma signal transduction. Alternative splicing results in multiple transcript variants.

Research Area: Cancer, Cell biology, Epigenetics and nuclear signaling, Signal transduction

Synonyms: Tyrosine-protein kinase JAK1 , EC 2.7.10.2, Janus kinase 1, JAK-1, Tyrosine-protein kinase JAK1, EC 2.7.10.2, Janus kinase 1, JAK-1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year