Jak3 (Phospho-Tyr980/981) Rabbit polyclonal antibody, anti-human, mouse

Jak3 (Phospho-Tyr980/981) Rabbit polyclonal antibody, anti-human, mouse

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In stock
SKU
BT-AP10727
Catalog Number: BT-AP10727
Size(s): 20μL, 50μL, 100μL
Isotype: Rabbit IgG
Reactivity: human, mouse
Application(s): WB
Datasheet
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Background:
The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).

Research Area: Cancer, Epigenetics and nuclear signaling, Signal transduction

Synonyms: Jak3 , Tyr980/981 , Tyrosine-protein kinase JAK3, EC 2.7.10.2, Janus kinase 3, JAK-3, Leukocyte janus kinase, L-JAK

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year
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