Perforin 1 polyclonal, anti-human
€470.00
In stock
SKU
AC-AP73975
Background:
Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Plays an important role in killing other cells that are recognized as non-self by the immune system, e.g. in transplant rejection or some forms of autoimmune disease. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes.
Other Names:
Perforin-1 (P1) (Cytolysin) (Lymphocyte pore-forming protein) (PFP)
Antigen Type: synthetic peptide
Antigen Type: PRF1
Gene ID: 5551
Primary Accession: P14222
Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Plays an important role in killing other cells that are recognized as non-self by the immune system, e.g. in transplant rejection or some forms of autoimmune disease. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes.
Other Names:
Perforin-1 (P1) (Cytolysin) (Lymphocyte pore-forming protein) (PFP)
Antigen Type: synthetic peptide
Antigen Type: PRF1
Gene ID: 5551
Primary Accession: P14222
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