JARID1A Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP1192a
Background:
The protein encoded by this gene is a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein which regulates cell proliferation. This protein also interacts with rhombotin-2 which functions distinctly in erythropoiesis and in T-cell leukemogenesis. Rhombotin-2 is thought to either directly affect the activity of the encoded protein or may indirectly modulate the functions of the retinoblastoma protein by binding to this protein.
Other Names:
Lysine-specific demethylase 5A, 11411-, Histone demethylase JARID1A, Jumonji/ARID domain-containing protein 1A, Retinoblastoma-binding protein 2, RBBP-2, KDM5A, JARID1A, RBBP2, RBP2
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1192a was selected from the N-term region of human JARID1A. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: KDM5A (HGNC:9886)
Gene ID: 5927
Primary Accession: P29375
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The protein encoded by this gene is a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein which regulates cell proliferation. This protein also interacts with rhombotin-2 which functions distinctly in erythropoiesis and in T-cell leukemogenesis. Rhombotin-2 is thought to either directly affect the activity of the encoded protein or may indirectly modulate the functions of the retinoblastoma protein by binding to this protein.
Other Names:
Lysine-specific demethylase 5A, 11411-, Histone demethylase JARID1A, Jumonji/ARID domain-containing protein 1A, Retinoblastoma-binding protein 2, RBBP-2, KDM5A, JARID1A, RBBP2, RBP2
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1192a was selected from the N-term region of human JARID1A. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: KDM5A (HGNC:9886)
Gene ID: 5927
Primary Accession: P29375
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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