Jarid1b polyclonal, anti- antibody
€215.00
In stock
SKU
AC-ABV11388-50
Catalog Number: AC-ABV11388-50
Size: 50 µl
Host: Rabbit IgG
Applications: WB, E
Datasheet
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Size: 50 µl
Host: Rabbit IgG
Applications: WB, E
Datasheet
Request Information
Background:
JARID1b is a histone demethylase which specifically demethylates mono-, di, and trimethylated lysine 4 of histone H3. It acts as a transcriptional repressor for the tumor suppressor genes BRCA1 and HOXA5 and has been associated with breast cancer development. In contrast, in melanoma JARID1b itself may function as a tumor suppressor.
Other Names:
CT31, PLU1, PUT1, RBBP2H1, RBP2-like
Primary Accession: Q9UGL1
Gene Name: KDM5B
Gene ID: 10765
JARID1b is a histone demethylase which specifically demethylates mono-, di, and trimethylated lysine 4 of histone H3. It acts as a transcriptional repressor for the tumor suppressor genes BRCA1 and HOXA5 and has been associated with breast cancer development. In contrast, in melanoma JARID1b itself may function as a tumor suppressor.
Other Names:
CT31, PLU1, PUT1, RBBP2H1, RBP2-like
Primary Accession: Q9UGL1
Gene Name: KDM5B
Gene ID: 10765
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